It owes its name to the five cannons that defended Nafplio in the west in combination with Bourtzi and was constructed by Venetians in the late 15th century.

It dates from the 2nd Venetian Occupation (1687-1715) and was rebuilt in 1831 with the addition of the second floor. One of the largest houses in town with impressive interior decorations, it was the residence of Count Von Armansperg.

Harvard University’s Center for Hellenic Studies in Greece (CHS GR) is an international center of learning, research and outreach. Fostering collaboration among scholars from all countries to promote a greater understanding of Hellenic civilization, the Nafplion Center offers full access -free of charge- to Harvard University’s digital resources.

It is the oldest mosque in the city, probably from the end of the 16th century.
In the years of the 2nd Venetian Occupation it was converted into a catholic church. From 1828 until 1833 it housed a school and later it was used as a theatre and a cinema called "Trianon". Today it houses the Municipal Theatre of Nafplio.

Built around 1730, it was originally used as a mosque and is characteristic for late Ottoman architecture. After the end of the Greek Independence war it housed the Greek Parliament (1825-1826). It is currently a conference hall. The Art Gallery of the Municipality of Nafplio is housed on the ground floor.

It is a single-naved church with a dome and was built in 1702. The first Greek Governor I. Kapodistrias was assassinated here in 1831. One of the two assassins was chased and lynched by the furious crowd. At the small square there are two Turkish fountains from the 18th century.

Metropolitan Church of Aghios Georgios.

One of the oldest and most important churches in the city. Built at the beginning of the 16th century, it was converted into a mosque by Turks, into a church again by Venetians and during the 2nd Turkish Occupation it became a mosque once more. Since 1822 it is an Orthodox Church. The paintings in western style date from the beginning of the 18th century.

A 1905 neo-classical building that served as a residence, a hospital, a clinic, a military headquarters and finally a tavern. Since 2004 it houses the Nafplio National Gallery Annex.

Built in 1713 as a warehouse for the Venetian Navy, it became a military caserne. During the German Occupation it housed the German Interrogation Office and today it serves as an Archaeological Museum holding a rich collection of finds from prehistoric until roman times.